Houston, Texas--(Newsfile Corp. - January 12, 2026) - Cannabis Bioscience International Holdings, Inc. (OTCID: CBIH), a public company trading on the OTC Markets under the ticker symbol CBIH, announced today the launch of its Evidence Sprint 2026, an intensive execution phase designed to turn cannabinoid science into usable medical evidence: protocols, operational collaboration, and projects ready for competitive funding.

CBIH confirms receipt of a communication from the Centers for Medicare & Medicaid Services (CMS) acknowledging Company's meeting request with CMS Administrator Dr. Mehmet Oz and placing the request within the formal institutional coordination channel, with an update expected as the internal process progresses. For CBIH, this step strengthens a strategic opportunity: to elevate public and institutional dialogue with a medical focus, advance evidence-based education, and promote serious standards for the responsible development of cannabinoid-derived therapies.

In parallel, CBIH is executing a multi-sector offensive to turn conversation into action through formal communications, calls, and direct coordination with pharmaceutical companies, healthcare organizations, institutional teams, and legislative offices, with a clear goal: moving from "interest" to technical working sessions and from "intention" to verifiable work plans.

On the financial front, the market is entering a phase of progressive normalization: as the federal framework evolves, more institutions and compliance teams are reassessing and building capabilities to serve the ecosystem under more structured risk and control models. In parallel, legislative initiatives such as the SAFER Banking Act continue to point toward greater clarity for financial services in the sector, reinforcing momentum toward broader integration.

"This is not about headlines; it is about evidence that withstands clinical and institutional review," said Rosangel Andrades, MD, CBIH R&D Director. "Our focus is to execute verifiable science: formulation, safety, delivery methods, and measurable outcomes, supported by compliance and real collaboration."

On the funding side, CBIH reported that it is giving full priority to its grants agenda through a pipeline-and-execution approach: identifying calls, aligning eligibility, structuring competitive proposals, and activating institutional partners. This momentum aligns with a tangible trend: meaningful funding is already being allocated to research and education related to medical cannabis and cannabinoids. For example, the California Department of Cannabis Control awarded nearly $30 million in competitive grants to nine academic institutions for 22 projects, marking the third round of this program and bringing the total to nearly $80 million since 2020.

"CBIH is in execution mode: institutions, grants, and evidence," said Jennifer Salguero, Biologist, PhD in Science, Chief Patent Officer, CBIH in Science, University of São Paulo, Brazil. "Our goal is to raise the standard and turn the therapeutic potential of cannabinoids into strong, responsible research that is useful for patients, physicians, and institutions."

CBIH reiterated that its platform integrates investigational formulations, a standardization-oriented vision, and a strategic approach focused on strengthening alliances with institutions and healthcare stakeholders that prioritize rigor, compliance, and outcomes, with a summary of its completed patent portfolio included in the table attached hereto.

FORWARD-LOOKING STATEMENTS

This press release may contain forward-looking statements. The words "believe," "expect," "should," "intend," "estimate," "projects," variations of such words and similar expressions identify forward-looking statements, but their absence does not mean that a statement is not a forward-looking statement. These forward-looking statements are based upon the Company's current expectations and are subject to a number of risks, uncertainties, and assumptions. The Company undertakes no obligation to update any forward-looking statements, whether as a result of new information, future events, or otherwise. Among the important factors that could cause actual results to differ significantly from those expressed or implied by such forward-looking statements are risks that are detailed in the Company's filings, which are on file at www.OTCmarkets.com.

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