Washington, DC 20549


                                    FORM 8-K

                                 CURRENT REPORT
                       PURSUANT TO SECTION 13 OR 15(d) OF
                           THE SECURITIES ACT OF 1934

         Date of report (Date of earliest event reported): June 4, 2002

                               CYTOGEN CORPORATION
               (Exact Name of Registrant as Specified in Charter)

          Delaware                      000-14879               222322400
(State or Other Jurisdiction     (Commission File Number)       (IRS Employer
      of Incorporation)                                      Identification No.)

600 College Road East, CN 5308, Princeton, NJ                         08540
(Address of Principal Executive Offices)                            (Zip Code)

                                 (609) 750-8200
                         (Registrant's telephone number,
                              including area code)

          (Former Name or Former Address, if Changed Since Last Report)

         Item 5.     Other Events.

         On June 4, 2002, Cytogen Corporation (the "Company")  announced that it
had issued and sold 4,166,700  shares (the "Shares") of its common stock,  $0.01
par value per share, to the State of Wisconsin  Investment  Board ("SWIB"),  the
Company's largest current shareholder, at a price of $1.20 per share. The Shares
were registered under the Company's existing Registration  Statement on Form S-3
(File No. 333-72226) (the "Registration  Statement"),  which permits the Company
to issue up to an  aggregate  of  10,000,000  shares  of  common  stock  and was
declared effective by the Securities and Exchange  Commission (the "Commission")
on November 5, 2001.  On June 4, 2002,  the  Company  filed a second  prospectus
supplement to the  prospectus  dated as of October 25, 2001 with the  Commission
relating to such  issuance  and sale of Shares to SWIB.  The Company  previously
issued 2,970,665  registered  shares of common stock to SWIB on January 22, 2002
under the Registration Statement.

         A copy of the Company's press release  announcing the issuance and sale
of the Shares to SWIB is  attached  hereto as Exhibit  99.1 and is  incorporated
herein  by  reference.  The  foregoing  description  of such  press  release  is
qualified in its entirety by reference to such document.

         Item 7.     Financial Statements, Pro Forma Financial Information and

         (c) Exhibits.

                Exhibit No.      Description
                -----------      -----------

                   99.1          Press Release, dated June 4, 2002, issued by
                                 the Company


                  Pursuant to the requirements of the Securities Exchange Act of
1934,  the  registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.

                                              Cytogen Corporation

                                              By: /s/ Lawrence R. Hoffman
                                                 Lawrence R. Hoffman,
                                                 Chief Financial Officer

Date:  June 4, 2002