Washington, DC 20549


                                    FORM 8-K

                                 CURRENT REPORT

                       Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934

         Date of report (Date of earliest event reported): May 24, 2002

                         CYTOGEN RETIREMENT SAVINGS PLAN
               (Exact Name of Registrant as Specified in Charter)

           Delaware                     000-14879                 222322400
 (State or Other Jurisdiction    (Commission File Number)       (IRS Employer
       of Incorporation)                                     Identification No.)

600 College Road East, CN 5308, Princeton, NJ                          08540
(Address of Principal Executive Offices)                             (Zip Code)

                                 (609) 750-8200
                         (Registrant's telephone number,
                              including area code)

          (Former Name or Former Address, if Changed Since Last Report)

         Item 4.   Changes in Registrant's Certifying Accountant.

     On May 20,  2002,  the  Board of  Directors  of  Cytogen  Corporation  (the
"Company"),  the Sponsor of the Cytogen  Retirement  Savings Plan (the  "Plan"),
dismissed Arthur Andersen LLP ("Arthur  Andersen") as the Company's  independent
public  accountants  and engaged  KPMG LLP  ("KPMG")  to serve as the  Company's
independent public accountants for the fiscal year ending December 31, 2002. The
appointment  of KPMG,  which was  recommended  to the Board of  Directors of the
Company by its Audit Committee, was effective immediately.  Accordingly,  Arthur
Andersen was also dismissed as the Plan's  independent  public  accountants  and
KPMG was appointed auditors of the Plan for the year ended December 31, 2001.

     The decision to change auditors was not the result of any disagreement with
Arthur  Andersen  with  respect  to  any  reporting  or  disclosure  requirement
applicable to the Plan. The reports of Arthur  Andersen on the Plan's  financial
statements for the fiscal years ended December 31, 2000 and 1999 did not contain
an adverse opinion or a disclaimer of opinion and were not qualified or modified
as to  uncertainty,  audit scope,  or accounting  principles.  During the fiscal
years ended  December  31, 2000 and 1999 and the interim  period from January 1,
2001 through May 24, 2002, there were no  disagreements  with Arthur Andersen on
any matter of accounting principles or practices, financial statement disclosure
or auditing scope and procedure  which,  if not resolved to the  satisfaction of
Arthur  Andersen,  would have caused  Arthur  Andersen to make  reference to the
matter in their report.  During such fiscal years and interim  period there were
no "reportable  events",  as that term is defined in paragraph (a)(1)(v) of Item
304 of Securities and Exchange Commission Regulation S-K ("Regulation S-K").

     The Plan provided Arthur Andersen with a copy of the foregoing disclosures.
Attached as Exhibit 16.1 to this Current  Report on Form 8-K is a copy of Arthur
Andersen's letter dated May 24, 2002 stating its agreement with such statements.

     During the fiscal  years ended  December  31, 2000 and 1999 and the interim
period  through May 24,  2002,  the Company did not consult KPMG with respect to
the  application  of accounting  principles to a specified  transaction,  either
completed  or proposed,  or the type of audit  opinion that might be rendered on
the Plan's financial  statements,  or on any other matters or reportable  events
listed in Item 304(a)(2)(i) and (ii) of Regulation S-K.

         Item 7.   Financial Statements, Pro Forma Financial Information and

         (c) Exhibits.

               Exhibit No.      Description of Exhibits
               -----------      -----------------------

               16.1             Letter from Arthur Andersen LLP regarding change
                                in certifying accountant dated May 24, 2002.


                  Pursuant to the requirements of the Securities Exchange Act of
1934, the registrant has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.

                                    Cytogen Retirement Savings Plan

                                    By:  /s/ H. Joseph Reiser
                                        H. Joseph Reiser
                                        President and Chief Executive Officer

Date:  May 24, 2002