FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person *   Abingworth Management LTD 2. Date of Event Requiring Statement (Month/Day/Year) 03/04/2005 3. Issuer Name and Ticker or Trading Symbol Solexa, Inc. [SLXA] (Last) (First) (Middle) 38 JERMYN STREET 4. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director __X__ 10% Owner _____ Officer (give title below) _____ Other (specify below) 5. If Amendment, Date Original Filed(Month/Day/Year) (Street) LONDON, X0 SW1Y 6DN 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Beneficially Owned

1.Title of Security (Instr. 4) 2. Amount of Securities Beneficially Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5) Common Stock 2,266,436 (1) I by Abingworth Bioventures II S.E.C.A. V i.l Common Stock 363,278 (2) I By Abingworth Bioventures II A L.P. Common Stock 935,791 (3) I By Abingworth Bioventures III A L.P. Common Stock 571,244 (4) I By Abingworth Bioventures IIIB L.P. Common Stock 342,179 (5) I By Abingworth Bioventures IIIC L.P. Common Stock 14,913 (6) I By Abingworth Bioventures III Executives LP

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.			SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Abingworth Management LTD 38 JERMYN STREET LONDON, X0 SW1Y 6DN	Â	  X	Â	Â

Signatures

James Abell, Director, Abingworth Management Ltd.		03/11/2005
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	These shares are owned by Abingworth Bioventures II SICAV (i.l.) of which Abingworth Management Ltd is the Investment Adviser.
(2)	These shares are owned by Abingworth Bioventures IIA L.P. of which Abingworth Management Ltd. is the Manager.
(3)	These shares are owned by Abingworth Bioventures IIIA L.P. of which Abingworth Management Ltd. is the Manager.
(4)	These shares are owned by Abingworth Bioventures IIIB L.P. of which Abingworth Management Ltd. is the Manager.
(5)	These shares are owned by Abingworth Bioventures IIIC L.P. of which Abingworth Management Ltd. is the Manager.
(6)	These shares are owned by Abingworth Bioventures III Executives L.P. of which Abingworth Management Ltd. is the Manager.

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