Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
KUMARIA SHYAM K
   2. Issuer Name and Ticker or Trading Symbol
SPECTRUM PHARMACEUTICALS INC [SPPI] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Vice President Finance
(Last)
(First)
(Middle)
157 TECHNOLOGY DRIVE		 3. Date of Earliest Transaction (Month/Day/Year)
04/23/2009
(Street)

IRVINE, CA 92618		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy) $ 6.2 04/23/2009   D     50,000   (1) 12/09/2013 Common Stock 50,000 $ 1.15 (2) 0 D  
Stock Option (Right to Buy) $ 6.05 04/23/2009   D     75,000   (3) 07/10/2014 Common Stock 75,000 $ 1.15 (2) 0 D  
Common Stock (Right to Buy) $ 6.66 04/23/2009   D     50,000   (4) 01/03/2015 Common Stock 50,000 $ 1.15 (2) 0 D  
Common Stock (Right to Buy) $ 5.91 04/23/2009   D     100,000   (5) 12/08/2016 Common Stock 100,000 $ 1.15 (2) 0 D  
Common Stock (Right to Buy) $ 6.9 04/23/2009   D     75,000   (6) 07/20/2017 Common Stock 75,000 $ 1.15 (2) 0 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
KUMARIA SHYAM K
157 TECHNOLOGY DRIVE
IRVINE, CA 92618		       Vice President Finance  

Signatures

 /S/ Shyam Kumaria   04/27/2009
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The shares underlying this stock option vested in equal 25% increments every 6 months from the Grant Date of December 9, 2003 over 2 years. As of April 23, 2009, the shares underlying this stock option had vested.
(2) This stock option was cancelled by the mutual agreement of the reporting person and the issuer pursuant to the issuer's tender offer filed on Schedule TO (the "Schedule TO") dated March 23, 2009, as filed with the Securities and Exchange Commission (the "SEC") on March 23, 2009, as amended by Amendment No. 1 and Amendment No. 2 to Schedule TO filed with the SEC on April 9, 2009 and April 24, 2009, respectively.
(3) The shares underlying this stock option vested in equal increments every six months from the Grant Date of July 10, 2004 over 2 years. As of April 23, 2009, the shares underlying this stock option had vested.
(4) The shares underlying this stock option vested in equal 25% increments every 12 months commencing on the Grant Date of January 3, 2005 over 3 years. As of April 23, 2009, the shares underlying this stock option had vested.
(5) The shares underlying this stock option grant vested in equal 25% increments commencing on the Grant Date of December 8, 2006 over 3 years. As of April 23, 2009, 75,000 shares underlying this stock option had vested.
(6) The shares underlying this stock option vested in equal 25% increments commencing on the Grant Date of July 20, 2007 over 3 years. As of April 23, 2009, 37,500 of the shares underlying this stock option had vested.

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