Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  CHL Medical Partners II, L.P.
2. Date of Event Requiring Statement (Month/Day/Year)
05/30/2007
3. Issuer Name and Ticker or Trading Symbol
AMICUS THERAPEUTICS INC [FOLD]
(Last)
(First)
(Middle)
C/O GREGORY M. WEINHOFF, 1055 WASHINGTON BLVD.
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

STAMFORD, CT 06901
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 124,916
D
 
Common Stock 8,416
I
CHL Medical Partners II Side Fund, L.P. (1)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Series A Convertible Preferred Stock 04/15/2002   (2) Common Stock 83,278 (2) $ 0 (2) D  
Series A Convertible Preferred Stock 04/15/2002   (2) Common Stock 5,611 (2) $ 0 (2) I CHL Medical Partners II Side Fund, L.P. (1)
Series A Convertible Preferred Stock 07/15/2002   (2) Common Stock 333,111 $ 0 (2) D  
Series A Convertible Preferred Stock 07/15/2002   (2) Common Stock 22,444 $ 0 (2) I CHL Medical Partners II Side Fund, L.P. (1)
Series B Convertible Preferred Stock 05/04/2005   (2) Common Stock 734,803 (2) $ 0 (2) D  
Series B Convertible Preferred Stock 05/04/2005   (2) Common Stock 49,509 (2) $ 0 (2) I CHL Medical Partners II Side Fund, L.P. (1)
Series B Convertible Preferred Stock 04/18/2006   (2) Common Stock 11,182 (2) $ 0 (2) D  
Series B Convertible Preferred Stock 04/18/2006   (2) Common Stock 753 (2) $ 0 (2) I CHL Medical Partners II Side Fund, L.P. (1)
Series C Convertible Preferred Stock 08/16/2005   (2) Common Stock 247,850 (2) $ 0 (2) D  
Series C Convertible Preferred Stock 08/16/2005   (2) Common Stock 16,699 (2) $ 0 (2) I CHL Medical Partners II Side Fund, L.P. (1)
Series C Convertible Preferred Stock 04/17/2006   (2) Common Stock 247,850 (2) $ 0 (2) D  
Series C Convertible Preferred Stock 04/17/2006   (2) Common Stock 16,699 (2) $ 0 (2) I CHL Medical Partners II Side Fund, L.P. (1)
Series D Convertible Preferred Stock 09/13/2006   (2) Common Stock 96,233 (2) $ 0 (2) D  
Series D Convertible Preferred Stock 09/13/2006   (2) Common Stock 6,484 (2) $ 0 (2) I CHL Medical Partners II Side Fund, L.P. (1)
Series D Convertible Preferred Stock 03/09/2007   (2) Common Stock 96,233 (2) $ 0 (2) D  
Series D Convertible Preferred Stock 03/09/2007   (2) Common Stock 6,484 (2) $ 0 (2) I CHL Medical Partners II Side Fund, L.P.

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
CHL Medical Partners II, L.P.
C/O GREGORY M. WEINHOFF
1055 WASHINGTON BLVD.
STAMFORD, CT 06901
    X    

Signatures

CHL MEDICAL PARTNERS II, L.P. By: Collinson, Howe & Lennox II, LLC, Its General Partner By: /s/ Gregory Weinhoff, Vice President 05/30/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These shares are owned by CHL Medical Partners II Side Fund, L.P., which is under common control with CHL Medical Partners II, L.P. Collinson, Howe & Lennox II, L.L.C. serves as the sole general partner of CHL Medical Partners II Side Fund, L.P. and CHL Medical Partners II, L.P. and is the indirect beneficial owner of these shares. CHL Medical Partners II, L.P. disclaims beneficial ownership of such shares except to the extent of its pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of the shares for purposes of section 16 or for any other purpose.
(2) Each share is convertible and will automatically convert on a 1-for-1 basis into the Issuer's common stock upon the closing of the Issuer's initial public offering of common stock pursuant to an effective registration statement filed with the U.S. Securities and Exchange Commission. These shares have no expiration date.

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