SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                                  SCHEDULE 13G
                                 (Rule 13d-102)

             INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
           TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED
                            PURSUANT TO RULE 13d-2(b)

                               (Amendment No. 3)*

                              Array BioPharma Inc.
--------------------------------------------------------------------------------
                                (Name of Issuer)

                                  Common Stock
--------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    04269X105
--------------------------------------------------------------------------------
                                 (CUSIP Number)

                               December 31, 2008
                                (See Item 2(a))
--------------------------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

      |_|   Rule 13d-1(b)
      [X]   Rule 13d-1(c)
      |_|   Rule 13d-1(d)

                              (Page 1 of 17 Pages)

----------
* The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

      The information required in the remainder of this cover page shall not be
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).



CUSIP No. 04269X105                   13G                           Page 2 of 17

--------------------------------------------------------------------------------
1.    NAME OF REPORTING PERSONS
      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

      Deerfield Capital, L.P.
--------------------------------------------------------------------------------
2.    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*                  (a) |_|
                                                                         (b) |X|

--------------------------------------------------------------------------------
3.    SEC USE ONLY


--------------------------------------------------------------------------------
4.    CITIZENSHIP OR PLACE OF ORGANIZATION

      Delaware
--------------------------------------------------------------------------------
               5. SOLE VOTING POWER

                  0
               -----------------------------------------------------------------
  NUMBER OF    6. SHARED VOTING POWER
   SHARES
 BENEFICIALLY     7,580,680*
  OWNED BY     -----------------------------------------------------------------
    EACH       7. SOLE DISPOSITIVE POWER
  REPORTING
   PERSON         0
    WITH       -----------------------------------------------------------------
               8. SHARED DISPOSITIVE POWER

                  7,580,680*
--------------------------------------------------------------------------------
9.    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

      7,580,680*
--------------------------------------------------------------------------------
10.   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*  |_|


--------------------------------------------------------------------------------
11.   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

      9.98%*
--------------------------------------------------------------------------------
12.   TYPE OF REPORTING PERSON*

      PN
--------------------------------------------------------------------------------

*The provisions of warrants beneficially owned by the reporting person restrict
the exercise of such warrants to the extent that, upon such exercise, the
numbers of shares then beneficially owned by the holder and its affiliates and
any other person or entities with which such holder would constitute a Section
13(d) "group" would exceed 9.98% of the total number of shares of the issuer
then outstanding (the "Ownership Cap"). Accordingly, notwithstanding the number
of shares reported, the reporting person disclaims beneficial ownership of the
shares underlying such warrants to the extent beneficial ownership of such
shares would cause all reporting persons hereunder, in the aggregate, to exceed
the Ownership Cap.



CUSIP No. 04269X105                   13G                           Page 3 of 17

--------------------------------------------------------------------------------
1.    NAME OF REPORTING PERSONS
      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

      Deerfield Partners, L.P.
--------------------------------------------------------------------------------
2.    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*                  (a) |_|
                                                                         (b) |X|

--------------------------------------------------------------------------------
3.    SEC USE ONLY


--------------------------------------------------------------------------------
4.    CITIZENSHIP OR PLACE OF ORGANIZATION

      Delaware
--------------------------------------------------------------------------------
               5. SOLE VOTING POWER

                  0
               -----------------------------------------------------------------
  NUMBER OF    6. SHARED VOTING POWER
   SHARES
 BENEFICIALLY     1,467,611
  OWNED BY     -----------------------------------------------------------------
    EACH       7. SOLE DISPOSITIVE POWER
  REPORTING
   PERSON         0
    WITH       -----------------------------------------------------------------
               8. SHARED DISPOSITIVE POWER

                  1,467,611
--------------------------------------------------------------------------------
9.    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

      1,467,611
--------------------------------------------------------------------------------
10.   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*  |_|


--------------------------------------------------------------------------------
11.   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

      3.08%
--------------------------------------------------------------------------------
12.   TYPE OF REPORTING PERSON*

      PN
--------------------------------------------------------------------------------



CUSIP No. 04269X105                   13G                           Page 4 of 17

--------------------------------------------------------------------------------
1.    NAME OF REPORTING PERSONS
      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

      Deerfield Special Situations Fund, L.P.
--------------------------------------------------------------------------------
2.    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*                  (a) |_|
                                                                         (b) |X|

--------------------------------------------------------------------------------
3.    SEC USE ONLY


--------------------------------------------------------------------------------
4.    CITIZENSHIP OR PLACE OF ORGANIZATION

      Delaware
--------------------------------------------------------------------------------
               5. SOLE VOTING POWER

                  0
               -----------------------------------------------------------------
  NUMBER OF    6. SHARED VOTING POWER
   SHARES
 BENEFICIALLY     113,069
  OWNED BY     -----------------------------------------------------------------
    EACH       7. SOLE DISPOSITIVE POWER
  REPORTING
   PERSON         0
    WITH       -----------------------------------------------------------------
               8. SHARED DISPOSITIVE POWER

                  113,069
--------------------------------------------------------------------------------
9.    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

      113,069
--------------------------------------------------------------------------------
10.   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*  |_|


--------------------------------------------------------------------------------
11.   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

      0.24%
--------------------------------------------------------------------------------
12.   TYPE OF REPORTING PERSON*

      PN
--------------------------------------------------------------------------------



CUSIP No. 04269X105                   13G                           Page 5 of 17

--------------------------------------------------------------------------------
1.    NAME OF REPORTING PERSONS
      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

      Deerfield Management Company, L.P.
--------------------------------------------------------------------------------
2.    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*                  (a) |_|
                                                                         (b) |X|

--------------------------------------------------------------------------------
3.    SEC USE ONLY


--------------------------------------------------------------------------------
4.    CITIZENSHIP OR PLACE OF ORGANIZATION

      New York
--------------------------------------------------------------------------------
               5. SOLE VOTING POWER

                  0
               -----------------------------------------------------------------
  NUMBER OF    6. SHARED VOTING POWER
   SHARES
 BENEFICIALLY     3,169,166
  OWNED BY     -----------------------------------------------------------------
    EACH       7. SOLE DISPOSITIVE POWER
  REPORTING
   PERSON         0
    WITH       -----------------------------------------------------------------
               8. SHARED DISPOSITIVE POWER

                  3,169,166
--------------------------------------------------------------------------------
9.    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

      3,169,166
--------------------------------------------------------------------------------
10.   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*  |_|


--------------------------------------------------------------------------------
11.   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

      6.66%
--------------------------------------------------------------------------------
12.   TYPE OF REPORTING PERSON*

      PN
--------------------------------------------------------------------------------



CUSIP No. 04269X105                   13G                           Page 6 of 17

--------------------------------------------------------------------------------
1.    NAME OF REPORTING PERSONS
      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

      Deerfield International Limited
--------------------------------------------------------------------------------
2.    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*                  (a) |_|
                                                                         (b) |X|

--------------------------------------------------------------------------------
3.    SEC USE ONLY


--------------------------------------------------------------------------------
4.    CITIZENSHIP OR PLACE OF ORGANIZATION

      British Virgin Islands
--------------------------------------------------------------------------------
               5. SOLE VOTING POWER

                  0
               -----------------------------------------------------------------
  NUMBER OF    6. SHARED VOTING POWER
   SHARES
 BENEFICIALLY     2,953,547
  OWNED BY     -----------------------------------------------------------------
    EACH       7. SOLE DISPOSITIVE POWER
  REPORTING
   PERSON         0
    WITH       -----------------------------------------------------------------
               8. SHARED DISPOSITIVE POWER

                  2,953,547
--------------------------------------------------------------------------------
9.    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

      2,953,547
--------------------------------------------------------------------------------
10.   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*  |_|


--------------------------------------------------------------------------------
11.   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

      6.2%
--------------------------------------------------------------------------------
12.   TYPE OF REPORTING PERSON*

      CO
--------------------------------------------------------------------------------



CUSIP No. 04269X105                   13G                           Page 7 of 17

--------------------------------------------------------------------------------
1.    NAME OF REPORTING PERSONS
      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

      Deerfield Private Design Fund, L.P.
--------------------------------------------------------------------------------
2.    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*                  (a) |_|
                                                                         (b) |X|

--------------------------------------------------------------------------------
3.    SEC USE ONLY


--------------------------------------------------------------------------------
4.    CITIZENSHIP OR PLACE OF ORGANIZATION

      British Virgin Islands
--------------------------------------------------------------------------------
               5. SOLE VOTING POWER

                  0
               -----------------------------------------------------------------
  NUMBER OF    6. SHARED VOTING POWER
   SHARES
 BENEFICIALLY     2,298,000 (comprised of warrants to purchase shares of
  OWNED BY                   Common Stock)
    EACH       -----------------------------------------------------------------
  REPORTING    7. SOLE DISPOSITIVE POWER
   PERSON
    WITH          0
               -----------------------------------------------------------------
               8. SHARED DISPOSITIVE POWER

                  2,298,000 (comprised of warrants to purchase shares of
                             Common Stock)
--------------------------------------------------------------------------------
9.    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

      2,298,000 (comprised of warrants to purchase shares of Common Stock)
--------------------------------------------------------------------------------
10.   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*  |_|


--------------------------------------------------------------------------------
11.   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

      4.61%
--------------------------------------------------------------------------------
12.   TYPE OF REPORTING PERSON*

      CO
--------------------------------------------------------------------------------



CUSIP No. 04269X105                   13G                           Page 8 of 17

--------------------------------------------------------------------------------
1.    NAME OF REPORTING PERSONS
      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

      Deerfield Private Design International, L.P.
--------------------------------------------------------------------------------
2.    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*                  (a) |_|
                                                                         (b) |X|

--------------------------------------------------------------------------------
3.    SEC USE ONLY


--------------------------------------------------------------------------------
4.    CITIZENSHIP OR PLACE OF ORGANIZATION

      British Virgin Islands
--------------------------------------------------------------------------------
               5. SOLE VOTING POWER

                  0
               -----------------------------------------------------------------
  NUMBER OF    6. SHARED VOTING POWER
   SHARES
 BENEFICIALLY     3,702,000 (comprised of warrants to purchase shares of
  OWNED BY                   Common Stock)
    EACH       -----------------------------------------------------------------
  REPORTING    7. SOLE DISPOSITIVE POWER
   PERSON
    WITH          0
               -----------------------------------------------------------------
               8. SHARED DISPOSITIVE POWER

                  3,702,000 (comprised of warrants to purchase shares of
                             Common Stock)
--------------------------------------------------------------------------------
9.    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

      3,702,000 (comprised of warrants to purchase shares of Common Stock)
--------------------------------------------------------------------------------
10.   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*  |_|


--------------------------------------------------------------------------------
11.   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

      7.22%
--------------------------------------------------------------------------------
12.   TYPE OF REPORTING PERSON*

      CO
--------------------------------------------------------------------------------



CUSIP No. 04269X105                   13G                           Page 9 of 17

--------------------------------------------------------------------------------
1.    NAME OF REPORTING PERSONS
      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

      Deerfield Special Situations Fund International Limited
--------------------------------------------------------------------------------
2.    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*                  (a) |_|
                                                                         (b) |X|

--------------------------------------------------------------------------------
3.    SEC USE ONLY


--------------------------------------------------------------------------------
4.    CITIZENSHIP OR PLACE OF ORGANIZATION

      British Virgin Islands
--------------------------------------------------------------------------------
               5. SOLE VOTING POWER

                  0
               -----------------------------------------------------------------
  NUMBER OF    6. SHARED VOTING POWER
   SHARES
 BENEFICIALLY     215,619
  OWNED BY     -----------------------------------------------------------------
    EACH       7. SOLE DISPOSITIVE POWER
  REPORTING
   PERSON         0
    WITH       -----------------------------------------------------------------
               8. SHARED DISPOSITIVE POWER

                  215,619
--------------------------------------------------------------------------------
9.    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

      215,619
--------------------------------------------------------------------------------
10.   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*  |_|


--------------------------------------------------------------------------------
11.   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

      .45%
--------------------------------------------------------------------------------
12.   TYPE OF REPORTING PERSON*

      CO
--------------------------------------------------------------------------------



CUSIP No. 04269X105                   13G                          Page 10 of 17

--------------------------------------------------------------------------------
1.    NAME OF REPORTING PERSONS
      I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)

      James E. Flynn
--------------------------------------------------------------------------------
2.    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*                  (a) |_|
                                                                         (b) |X|

--------------------------------------------------------------------------------
3.    SEC USE ONLY


--------------------------------------------------------------------------------
4.    CITIZENSHIP OR PLACE OF ORGANIZATION

      United States
--------------------------------------------------------------------------------
               5. SOLE VOTING POWER

                  0
               -----------------------------------------------------------------
  NUMBER OF    6. SHARED VOTING POWER
   SHARES
 BENEFICIALLY     10,749,846*
  OWNED BY     -----------------------------------------------------------------
    EACH       7. SOLE DISPOSITIVE POWER
  REPORTING
   PERSON         0
    WITH       -----------------------------------------------------------------
               8. SHARED DISPOSITIVE POWER

                  10,749,846*
--------------------------------------------------------------------------------
9.    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

      10,749,846*
--------------------------------------------------------------------------------
10.   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*  |_|


--------------------------------------------------------------------------------
11.   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

      9.98%
--------------------------------------------------------------------------------
12.   TYPE OF REPORTING PERSON*

      IN
--------------------------------------------------------------------------------

*The provisions of warrants beneficially owned by the reporting person restrict
the exercise of such warrants to the extent that, upon such exercise, the
numbers of shares then beneficially owned by the holder and its affiliates and
any other person or entities with which such holder would constitute a Section
13(d) "group" would exceed 9.98% of the total number of shares of the issuer
then outstanding (the "Ownership Cap"). Accordingly, notwithstanding the number
of shares reported, the reporting person disclaims beneficial ownership of the
shares underlying such warrants to the extent beneficial ownership of such
shares would cause all reporting persons hereunder, in the aggregate, to exceed
the Ownership Cap.



CUSIP No. 04269X105                                                Page 11 of 17
          ---------

Item 1(a).  Name of Issuer:

            Array BioPharma Inc.
            --------------------------------------------------------------------
Item 1(b).  Address of Issuer's Principal Executive Offices:

            3200 Walnut Street
            Boulder, Colorado 80301
            --------------------------------------------------------------------
Item 2(a).  Name of Person Filing:

            James E. Flynn, Deerfield Capital, L.P., Deerfield Partners, L.P.,
            Deerfield Special Situations Fund, L.P., Deerfield Management
            Company, L.P., Deerfield International Limited, Deerfield Special
            Situations Fund International Limited Deerfield Private Design Fund,
            L.P., ("Private Design"); Deerfield Private Design International,
            L.P. ("Private Design International" and together with Private
            Design, the "Design Funds")

            The Design Funds became holders of Common Stock on June 20, 2008.
            --------------------------------------------------------------------
Item 2(b).  Address of Principal Business Office, or if None, Residence:

            James E. Flynn, Deerfield Capital, L.P., Deerfield Partners, L.P.
            Deerfield Special Situations Fund, L.P., Deerfield Private Design
            Fund, L.P., Deerfield Private Design International, L.P., Deerfield
            Management Company, L.P., 780 Third Avenue, 37th Floor, New York, NY
            10017 Deerfield International Limited, Deerfield Special Situations
            Fund International Limited c/o Bisys Management, Bison Court,
            Columbus Centre, P.O. Box 3460, Road Town, Tortola, British Virgin
            Islands
            --------------------------------------------------------------------
Item 2(c).  Citizenship:

            Mr. Flynn - United States citizen
            Deerfield Capital, L.P., Deerfield Partners, L.P., Deerfield
            Special Situations Fund, L.P. and Deerfield Private Design
            Fund, L.P. - Delaware limited partnerships Deerfield Management
            Company, L.P. - New York limited partnership Deerfield International
            Limited, Deerfield Special Situations Fund International Limited
            and Deerfield Private Design International, L.P. - British
            Virgin Islands corporations
            --------------------------------------------------------------------
Item 2(d).  Title of Class of Securities:

            Common Stock
            --------------------------------------------------------------------
Item 2(e).  CUSIP Number:

            04269X105
            --------------------------------------------------------------------

Item 3.     If This Statement is Filed Pursuant to Rule 13d-1(b), or 13d-2(b)
            or (c), Check Whether the Person Filing is a:

      (a)   |_| Broker or dealer registered under Section 15 of the Exchange
                Act.

      (b)   |_| Bank as defined in Section 3(a)(6) of the Exchange Act.

      (c)   |_| Insurance company as defined in Section 3(a)(19) of the Exchange
                Act.

      (d)   |_| Investment company registered under Section 8 of the Investment
                Company Act.



                                                                   Page 12 of 17

      (e)   |_| An investment adviser in accordance with Rule
                13d-1(b)(1)(ii)(E);

      (f)   |_| An employee benefit plan or endowment fund in accordance with
                Rule 13d-1(b)(1)(ii)(F);

      (g)   |_| A parent holding company or control person in accordance with
                Rule 13d-1(b)(1)(ii)(G);

      (h)   |_| A savings association as defined in Section 3(b) of the Federal
                Deposit Insurance Act;

      (i)   |_| A church plan that is excluded from the definition of an
                investment company under Section 3(c)(14) of the Investment
                Company Act;

      (j)   |_| Group, in accordance with Rule 13d-1(b)(1)(ii)(J).

Item 4.  Ownership.

      Provide the following information regarding the aggregate number and
percentage of the class of securities of the issuer identified in Item 1.

     (a) Amount beneficially owned:

         Deerfield Capital, L.P. - 7,580,680* shares(includes shares
         underlying 6,000,000 warrants)
         Deerfield Partners, L.P. - 1,467,611 shares
         Deerfield Special Situations Fund, L.P. - 113,069 shares
         Deerfield Management Company, L.P. - 3,169,166 shares
         Deerfield International Limited - 2,953,547 shares
         Deerfield Private Design Fund, L.P. - 2,298,000 (comprised of warrants
         to purchase shares of common stock)
         Deerfield Private Design International, L.P. - 3,702,000 (comprised of
         warrants to purchase shares of Common Stock)
         Deerfield Special Situations Fund International Limited -
         215,619 shares
         James E. Flynn - 10,749,846* shares (includes shares underlying
         6,000,000 warrants)
         -----------------------------------------------------------------------

     (b) Percent of class:

         Deerfield Capital, L.P. - 9.98%*
         Deerfield Partners, L.P. - 3.08%
         Deerfield Special Situations Fund, L.P. - .24%
         Deerfield Management Company, L.P. - 6.66%
         Deerfield International Limited - 6.2%
         Deerfield Private Design Fund, L.P. - 4.61%
         Deerfield Private Design International, L.P. 7.22%
         Deerfield Special Situations Fund International Limited - .45%
         James E. Flynn - 9.98%*
         -----------------------------------------------------------------------

     (c) Number of shares as to which such person has:

         (i)   Sole power to vote or to
               direct the vote                 All Reporting Persons - 0
                                               ------------------------,

* The provisions of warrants beneficially owned by the reporting person restrict
the exercise of such warrants to the extent that, upon such exercise, the
numbers of shares then beneficially owned by the holder and its affiliates and
any other person or entities with which such holder would constitute a Section
13(d) "group" would exceed 9.98% of the total number of shares of the issuer
then outstanding (the "Ownership Cap"). Accordingly, notwithstanding the number
of shares reported, the reporting person disclaims beneficial ownership of the
shares underlying such warrants to the extent beneficial ownership of such
shares would cause all reporting persons hereunder, in the aggregate, to exceed
the Ownership Cap.



                                                                   Page 13 of 17

         (ii)  Shared power to vote or to
               direct the vote                 Deerfield Capital,
                                               L.P. - 7,580,680
                                               Deerfield Partners,
                                               L.P. - 1,467,611
                                               Deerfield Special
                                               Situations Fund,
                                               L.P. - 113,069
                                               Deerfield
                                               Management Company,
                                               L.P. - 3,169,166
                                               Deerfield
                                               International
                                               Limited - 2,953,547
                                               Deerfield Private
                                               Design Fund,
                                               L.P. 2,298,000
                                               Deerfield Private
                                               Design International,
                                               L.P. 3,702,000
                                               Deerfield Special
                                               Situations Fund
                                               International
                                               Limited - 215,619
                                               James E. Flynn -
                                               10,749,846
                                               ------------------
         (iii) Sole power to dispose or to
               direct the disposition of       All Reporting Persons - 0

         (iv)  Shared power to dispose or to
               direct the disposition of       Deerfield Capital,
                                               L.P. - 7,580,680
                                               Deerfield Partners,
                                               L.P. - 1,467,611
                                               Deerfield Special
                                               Situations Fund,
                                               L.P. - 113,069
                                               Deerfield
                                               Management Company,
                                               L.P. - 3,032,058
                                               Deerfield
                                               International
                                               Limited - 2,953,547
                                               Deerfield Private
                                               Design Fund,
                                               L.P. 2,298,000
                                               Deerfield Private
                                               Design International,
                                               L.P. 3,702,000
                                               Deerfield Special
                                               Situations Fund
                                               International
                                               Limited - 215,619
                                               James E. Flynn -
                                               10,749,846
                                               ------------------

Item 5.  Ownership of Five Percent or Less of a Class.

      If this statement is being filed to report the fact that as of the date
hereof the reporting person has ceased to be the beneficial owner of more than
five percent of the class of securities check the following |_|.
      --------------------------------------------------------------------------



                                                                   Page 14 of 17

Item 6.  Ownership of More Than Five Percent on Behalf of Another Person.

      If any other person is known to have the right to receive or the power to
direct the receipt of dividends from, or the proceeds from the sale of, such
securities, a statement to that effect should be included in response to this
item and, if such interest relates to more than five percent of the class, such
person should be identified. A listing of the shareholders of an investment
company registered under the Investment Company Act of 1940 or the beneficiaries
of employee benefit plan, pension fund or endowment fund is not required.

      N/A
      --------------------------------------------------------------------------
Item 7.  Identification and Classification of the Subsidiary Which Acquired
         the Security Being Reported on by the Parent Holding Company or Control
         Person.

      If a parent holding company or Control person has filed this schedule,
pursuant to Rule 13d-1(b)(1)(ii)(G), so indicate under Item 3(g) and attach an
exhibit stating the identity and the Item 3 classification of the relevant
subsidiary. If a parent holding company or control person has filed this
schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating
the identification of the relevant subsidiary.

      N/A
      --------------------------------------------------------------------------



                                                                   Page 15 of 17

Item 8.  Identification  and  Classification  of Members of the Group.

      If a group has filed this schedule pursuant to ss.240.13d-1(b)(1)(ii)(J),
so indicate under Item 3(j) and attach an exhibit stating the identity and Item
3 classification of each member of the group. If a group has filed this schedule
pursuant to ss.240.13d-1(c) or ss.240.13d-1(d), attach an exhibit stating the
identity of each member of the group.

      See Exhibit B
      --------------------------------------------------------------------------
Item 9.  Notice of Dissolution of Group.

      Notice of dissolution of a group may be furnished as an exhibit stating
the date of the dissolution and that all further filings with respect to
transactions in the security reported on will be filed, if required, by members
of the group, in their individual capacity. See Item 5.

      N/A
      --------------------------------------------------------------------------

Item 10. Certifications.

      "By signing below I certify that, to the best of my knowledge and belief,
the securities referred to above were not acquired and are not held for the
purpose of or with the effect of changing or influencing the control of the
issuer of the securities and were not acquired and are not held in connection
with or as a participant in any transaction having such purpose or effect."


                                                                   Page 16 of 17

                                    SIGNATURE

      After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.

DEERFIELD CAPITAL, L.P.

By: J.E. Flynn Capital LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

DEERFIELD PARTNERS, L.P.

By: Deerfield Capital, L.P.

By: J.E. Flynn Capital LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

DEERFIELD SPECIAL SITUATIONS FUND, L.P.

By: Deerfield Capital, L.P.

By: J.E. Flynn Capital LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

DEERFIELD MANAGEMENT COMPANY, L.P.

By: Flynn Management LLC
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

DEERFIELD INTERNATIONAL LIMITED

By: Deerfield Management Company

By: Flynn Management LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

DEERFIELD PRIVATE DESIGN FUND, L.P.

By: Deerfield Capital, L.P.

By: J.E. Flynn Capital LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact


                                                                   Page 17 of 17

DEERFIELD PRIVATE DESIGN INTERNATIONAL, L.P.

By: Deerfield Capital, L.P.

By: J.E. Flynn Capital LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

DEERFIELD SPECIAL SITUATIONS FUND INTERNATIONAL LIMITED

By: Deerfield Management Company

By: Flynn Management LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

JAMES E. FLYNN

/s/ Darren Levine
-------------------------------
Darren Levine, Attorney-In-Fact

Date:  February 12, 2009



                                  Exhibit List

Exhibit A.     Joint Filing Agreement.

Exhibit B.     Item 8 Statement.

Exhibit C.(1)  Power of Attorney.

(1) Previously filed as Exhibit 24 to a Form 4 with regard to PAR Pharmaceutical
Companies, Inc. filed with the Commission on February 1, 2007 by Deerfield
Capital L.P.; Deerfield Partners, L.P.; Deerfield Management Company, L.P.;
Deerfield International Limited; Deerfield Special Situations Fund, L.P.;
Deerfield Special Situations Fund International Limited; and James E. Flynn.



                                    Exhibit A

                                    Agreement

      The undersigned agree that this Schedule 13G, and all amendments thereto,
relating to the Common Stock of Array BioPharma Inc. shall be filed on behalf of
the undersigned.

DEERFIELD CAPITAL, L.P.

By: J.E. Flynn Capital LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

DEERFIELD PARTNERS, L.P.

By: Deerfield Capital, L.P.

By: J.E. Flynn Capital LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

DEERFIELD SPECIAL SITUATIONS FUND, L.P.

By: Deerfield Capital, L.P.

By: J.E. Flynn Capital LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

DEERFIELD MANAGEMENT COMPANY, L.P.

By: Flynn Management LLC
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

DEERFIELD INTERNATIONAL LIMITED

By: Deerfield Management Company

By: Flynn Management LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

DEERFIELD PRIVATE DESIGN FUND, L.P.

By: Deerfield Capital, L.P.

By: J.E. Flynn Capital LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact



DEERFIELD PRIVATE DESIGN INTERNATIONAL, L.P.

By: Deerfield Capital, L.P.

By: J.E. Flynn Capital LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

DEERFIELD SPECIAL SITUATIONS FUND INTERNATIONAL LIMITED

By: Deerfield Management Company

By: Flynn Management LLC,
    General Partner

By: /s/ Darren Levine
    -------------------------------
    Darren Levine, Attorney-In-Fact

JAMES E. FLYNN

/s/ Darren Levine
-------------------------------
Darren Levine, Attorney-In-Fact




                                    Exhibit B

      Due to the relationships between them, the reporting persons hereunder may
be deemed to constitute a "group" with one another for purposes of Section
13(d)(3) of the Securities Exchange Act of 1934.