Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
Boisseau Philippe
  2. Issuer Name and Ticker or Trading Symbol
AMYRIS, INC. [AMRS]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
24 COURS MICHELET
3. Date of Earliest Transaction (Month/Day/Year)
12/02/2013
(Street)

92800 PUTEAUX, I0 
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock               13,617,212 I By Total Energies Nouvelles Activites USA (1)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
1.5% Senior Unsecured Convertible Note Due 2017 $ 7.0682 12/02/2013   J(2)     $ 15,000,000 (2)   (2)   (2) Common Stock $ 15,000,000 (2) $ 0 $ 0 (2) I By Total Energies Nouvelles Activites USA (1)
1.5% Senior Unsecured Convertible Note Due 2017 $ 3.08 12/02/2013   J(2)     $ 10,000,000 (2)   (2)   (2) Common Stock $ 10,000,000 (2) $ 0 $ 0 (2) I By Total Energies Nouvelles Activites USA (1)
1.5% Senior Unsecured Convertible Note Due 2017 $ 3.08 12/02/2013   J(2)     $ 20,000,000 (2)   (2)   (2) Common Stock $ 20,000,000 (2) $ 0 $ 0 (2) I By Total Energies Nouvelles Activites USA (1)
1.5% Senior Unsecured Convertible Note Due 2017 $ 7.0682 12/02/2013   J(2)     $ 24,047,816.63 (2)   (2)   (2) Common Stock $ 24,047,816.63 (2) $ 0 $ 0 (2) I By Total Energies Nouvelles Activites USA (1)
1.5% Senior Secured Convertible Note Due 2017 $ 7.0682 12/02/2013   P   $ 15,000,000 (3)     (3)   (3) Common Stock $ 15,000,000 (3) $ 0 $ 15,000,000 (3) I By Total Energies Nouvelles Activites USA (1)
1.5% Senior Secured Convertible Note Due 2017 $ 3.08 12/02/2013   P   $ 10,000,000 (4)     (4)   (4) Common Stock $ 10,000,000 (4) $ 0 $ 10,000,000 (4) I By Total Energies Nouvelles Activites USA (1)
1.5% Senior Secured Convertible Note Due 2017 $ 3.08 12/02/2013   P   $ 20,000,000 (5)     (5)   (5) Common Stock $ 20,000,000 (5) $ 0 $ 20,000,000 (5) I By Total Energies Nouvelles Activites USA (1)
1.5% Senior Secured Convertible Note Due 2017 $ 7.0682 12/02/2013   P   $ 24,047,816.63 (6)     (6)   (6) Common Stock $ 24,047,816.63 (6) $ 0 $ 24,047,816.63 (6) I By Total Energies Nouvelles Activites USA (1)

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Boisseau Philippe
24 COURS MICHELET
92800 PUTEAUX, I0 
  X   X    

Signatures

 /s/ Philippe Boisseau by Nicholas Khadder, Attorney-in-Fact   12/04/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Mr. Boisseau, a member of the Issuer's board of directors, is a member of the Executive Committee of Total S.A., the ultimate parent company of Total Energies Nouvelles Activites USA, and, as such, may be deemed to share voting or investment power over the securities held by Total Energies Nouvelles Activites USA. Mr. Boisseau holds no shares of the Issuer directly and disclaims beneficial ownership of the Common Stock, except to the extent of his pecuniary interest therein, if any.
(2) Note was cancelled pursuant to that certain Letter Agreement by and between the Reporting Person and the Issuer. The Issuer's obligations under the note were cancelled upon the issuance of a new 1.5% Senior Secured Convertible Note Due 2017.
(3) The principal amount of this note is $15,000,000.00. The note is convertible only in those circumstances described in the note. The Final Maturity Date as defined in the note is March 1, 2017.
(4) The principal amount of this note is $10,000,000.00. The note is convertible only in those circumstances described in the note. The Final Maturity Date as defined in the note is March 1, 2017.
(5) The principal amount of this note is $20,000,000.00. The note is convertible only in those circumstances described in the note. The Final Maturity Date as defined in the note is March 1, 2017.
(6) The principal amount of this note is $24,047,816.63. The note is convertible only in those circumstances described in the note. The Final Maturity Date as defined in the note is March 1, 2017.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.