Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Cheung Sylvia
 2. Date of Event Requiring Statement (Month/Day/Year)
04/01/2013		 3. Issuer Name and Ticker or Trading Symbol
ANIKA THERAPEUTICS INC [ANIK]
(Last)
(First)
(Middle)
32 WIGGINS AVENUE		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
CFO
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

BEDFORD, MA 01730		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock (ANIK) 7,050
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Incentive Stock Options   (1) 08/01/2015 Common Stock 10,000 $ 12.61 D  
Stock Appreciation Rights   (2) 01/31/2018 Common Stock 5,000 $ 10.99 D  
Stock Appreciation Rights   (3) 01/26/2020 Common Stock 35,000 $ 6.36 D  
Incentive Stock Options   (4) 01/18/2021 Common Stock 25,000 $ 6.98 D  
Incentive Stock Options   (5) 06/07/2021 Common Stock 24,193 $ 6.99 D  
Non-Qualified Stock Options   (5) 06/07/2021 Common Stock 807 $ 6.99 D  
Incentive Stock Options   (6) 01/25/2022 Common Stock 7,501 $ 9.1 D  
Non-Qualified Stock Options   (7) 01/25/2022 Common Stock 7,499 $ 9.1 D  
Incentive Stock Options   (8) 01/29/2023 Common Stock 17,305 $ 10.87 D  
Non-Qualified Stock Options   (9) 01/29/2023 Common Stock 27,695 $ 10.87 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Cheung Sylvia
32 WIGGINS AVENUE
BEDFORD, MA 01730		       CFO  

Signatures

/s/ Sylvia Cheung 04/01/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The stock options vest in four equal installments as follows: August 1, 2006, August 1, 2007, August 1, 2008, and August 1, 2009
(2) The stock appreciation rights vest in threw equal installments as follows: January 31, 2009, January 31, 2010 and January 31, 2011
(3) The stock appreciation rights vest in four equal installments as follows: January 26, 2011, January 26, 2012, January 26, 2013, and January 26, 2014
(4) The stock options vest in four equal installments as follows: January 18, 2012, January 18, 2013, January 18, 2014, and January 18, 2015
(5) The stock options vest in three equal installments as follows: March 1, 2012, January 1, 2013, and January 1, 2014
(6) The stock options vest as follows: 1 option at January 25, 2013, 3,375 options at January 25, 2014 and 3,375 options at January 25, 2015
(7) The stock options vest as follows: 3,749 options at January 25, 2013 and 3,750 options at January 25, 2014
(8) The stock options vest as follows: 2,046 options at January 29, 2015, 6,060 options at January 29, 2016 and 9,199 options at January 29, 2017
(9) The stock options vest as follows: 11,250 options at January 29, 2014, 9,204 options at January 29, 2015, 5,190 options at January 29, 2016, and 2,051 options at January 29, 2017

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