Filed pursuant to Rule 424(b)(3)
                                                   Commission File No. 333-67906


                    PROSPECTUS SUPPLEMENT DATED MAY 15, 2002
                     (TO PROSPECTUS DATED NOVEMBER 9, 2001)

                                  $175,000,000

                             CELL THERAPEUTICS, INC.

             5.75% Convertible Subordinated Notes due June 15, 2008
           and the common stock issuable upon conversion of the notes

     This Prospectus Supplement supplements the Prospectus dated November 9,
2001 (the "Prospectus") of Cell Therapeutics, Inc. ("CTI") relating to the
public offering, which is not being underwritten, and sale by certain
noteholders of CTI or by pledgees, donees, transferees or other successors in
interest that receive such notes as a gift, partnership distribution or other
non-sale related transfer (the "Selling Securityholders") of up to $175,000,000
of 5.75% convertible subordinated notes of CTI (the "Notes"). This Prospectus
Supplement should be read in conjunction with the Prospectus, and this
Prospectus Supplement is qualified by reference to the Prospectus except to the
extent that information herein contained supersedes the information contained in
the Prospectus. Capitalized terms used in this Prospectus Supplement and not
otherwise defined herein have the meanings specified in the Prospectus.


                             SELLING SECURITYHOLDER

     Recently, several entities acquired Notes, which they intend to sell under
the Prospectus. The following table provides certain information with respect to
the amount of Notes beneficially owned by each such entity, the percentage of
outstanding Notes and CTI common stock this represents, and the amount of Notes
to be registered for sale hereby. The table of Selling Securityholders in the
Prospectus is hereby amended to add the following:



                                                  Principal Amount at
                                                  Maturity of Notes      Percentage of     Number of Shares        Percentage of
                                                  Beneficially Owned        Notes           of Common Stock         Common Stock
       Name of Selling Securityholder              that may be sold       Outstanding     that may be sold(1)    Outstanding (2)(3)
       ------------------------------             -------------------    -------------    -------------------    ------------------
                                                                                                     
The James Campbell Corporation. ...............         $325,000               *                9,558                    *
The Estate of James Campbell ..................         $245,000               *                7,205                    *
Hotel Union & Hotel Industry of Hawaii
Pension Plan ..................................         $545,000               *               16,029                    *
Jefferies & Company, Inc. .....................          $12,000               *                  352                    *
American Samoa Government .....................          $51,000               *                1,500                    *
BP Amoco PLC Master Trust .....................       $1,527,000               *               44,911

-------------------
 *   Less than 1%.

(1)  Assumes conversion of all of the holder's notes at a conversion price of
     approximately $34.00 per share of common stock. However, this conversion
     price will be subject to adjustment as described in the Prospectus under
     "Description of Notes--Conversion Rights." As a result, the amount of
     common stock issuable upon conversion of the notes may increase or decrease
     in the future.

(2)  Calculated based on Rule 13d-3(d)(1)(i) of the Exchange Act using
     35,101,654 shares of common stock outstanding as of March 31, 2002.

(3)  Assumes that any other holders of notes, or any future transferees,
     pledgees, donees or successors of or from any such other holders of notes,
     do not beneficially own any common stock other than the common stock
     issuable upon conversion of the notes at the initial conversion rate.