Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  LUBIN DANIEL C
2. Date of Event Requiring Statement (Month/Day/Year)
01/25/2006
3. Issuer Name and Ticker or Trading Symbol
PATIENT INFOSYSTEMS INC [PATY]
(Last)
(First)
(Middle)
RADIUS VENTURE PARTNERS LLC, 400 MADISON AVE 8TH FLOOR
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

NEW YORK, NY 10017
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 6,431,776
I
By Fund (1) (2)
Common Stock 216,710
I
By Fund through escrow (2) (3)
Common Stock 92,929
I
By Fund through escrow (2) (4)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Call Option Equivalent (obligation to sell) 01/25/2006 07/25/2007 Common Stock 92,929 $ 0 I By Fund through escrow (5)

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
LUBIN DANIEL C
RADIUS VENTURE PARTNERS LLC
400 MADISON AVE 8TH FLOOR
NEW YORK, NY 10017
  X      

Signatures

/s/Daniel C. Lubin 02/06/2006
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Shares are owned of record by Radius Venture Partners I, L.P.
(2) Mr. Lubin, who has been designated to become one of the Issuer's directors, is a managing member of Radius Venture Partners, L.L.C., the general partner of Radius Venture Partners I, L.P. and therefore may be deemed to beneficially own the securities owned by Radius Venture Partners I, L.P. Mr. Lubin disclaims ownership of the reported securities except to the extent of his pecuniary interest therein. The reported number of shares represents the minimum number of shares issuable to Radius Venture Partners I, L.P. upon termination of the escrow arrangement and liquidation of the escrow account. In the event that the Reporting Person acquires a greater number of shares upon termination of the escrow agreement and liquidation of the escrow account, the Reporting Person will file a Form 4 reflecting the acquisition of additional shares.
(3) Shares are beneficially owned by Radius Venture Partners I, L.P. Represents shares held in escrow for the benefit of former stockholders of CCS Consolidated, Inc. whose shares were converted into shares of the Issuer as a result of a merger between CCS Consolidated, Inc. and the Issuer.
(4) Shares are beneficially owned by Radius Venture Partners I, L.P. Represents shares held in escrow for the benefit of another stockholder of the Issuer. The number of shares to be released to the other stockholder is contingent upon the occurrence of certain events as described in a letter agreement between the Issuer and the other stockholder. The reported number of shares represents the maximum number of shares issuable to Radius Venture Partners I, L.P. upon termination of the escrow arrangement and liquidation of the escrow account. These shares are subject to a call option in favor of the other stockholder as described in footnote (5).
(5) Another stockholder of the Issuer may, contingent upon the occurrence of certain events not in the control of Radius Venture Partners I, L.P. or the other stockholder, acquire the entire amount of the stock held in escrow as described in footnote (4), including the shares reported by Radius Venture Partners I, L.P. No additional consideration will be received by Radius Venture Partners I, L.P. to the extent the call option on these shares is exercised by the other stockholder. To the extent that the shares held in escrow may not be distributed to the other stockholder, the Reporting Person will report the partial or full expiration of the call option on Form 4.

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