Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  D. E. Shaw Valence Portfolios, L.L.C.
2. Date of Event Requiring Statement (Month/Day/Year)
03/04/2007
3. Issuer Name and Ticker or Trading Symbol
TAKE TWO INTERACTIVE SOFTWARE INC [TTWO]
(Last)
(First)
(Middle)
39TH FLOOR, TOWER 45, 120 WEST FORTY-FIFTH STREET
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
_____ Officer (give title below) __X__ Other (specify below)
See attached Exhibit.
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

NEW YORK, NY 10036
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 6,515,766
D (1) (2) (3)
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Call Option (right to buy)   (4) 01/16/2009 Common Stock 10,100 $ 20 D (1) (2) (3)  
Call Option (right to buy)   (4) 01/18/2008 Common Stock 19,900 $ 25 D (1) (2) (3)  
Call Option (right to buy)   (4) 01/18/2008 Common Stock 26,700 $ 30 D (1) (2) (3)  
Call Option (right to buy)   (4) 01/18/2008 Common Stock 1,000 $ 35 D (1) (2) (3)  
Put Option (obligation to buy)   (4) 01/18/2008 Common Stock 18,700 $ 15 D (1) (2) (3)  
Put Option (obligation to buy)   (4) 01/16/2009 Common Stock 17,100 $ 15 D (1) (2) (3)  
Put Option (obligation to buy)   (4) 03/16/2007 Common Stock 57,800 $ 17.5 D (1) (2) (3)  
Put Option (obligation to buy)   (4) 06/15/2007 Common Stock 113,100 $ 17.5 D (1) (2) (3)  
Put Option (obligation to buy)   (4) 06/15/2007 Common Stock 25,900 $ 20 D (1) (2) (3)  
Put Option (obligation to buy)   (4) 06/15/2007 Common Stock 13,100 $ 22.5 D (1) (2) (3)  
Put Option (obligation to buy)   (4) 03/16/2007 Common Stock 20,000 $ 20 D (1) (2) (3)  
Call Option (obligation to sell)   (4) 06/15/2007 Common Stock 66,800 $ 17.5 D (1) (2) (3)  
Call Option (obligation to sell)   (4) 01/16/2009 Common Stock 17,500 $ 17.5 D (1) (2) (3)  
Call Option (obligation to sell)   (4) 01/18/2008 Common Stock 50,000 $ 20 D (1) (2) (3)  
Call Option (obligation to sell)   (4) 01/16/2009 Common Stock 22,000 $ 15 D (1) (2) (3)  
Put Option (right to sell)   (4) 01/16/2009 Common Stock 15,200 $ 20 D (1) (2) (3)  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
D. E. Shaw Valence Portfolios, L.L.C.
39TH FLOOR, TOWER 45
120 WEST FORTY-FIFTH STREET
NEW YORK, NY 10036
      See attached Exhibit.
D. E. SHAW & CO, L.P.
39TH FLOOR, TOWER 45
120 WEST FORTY-FIFTH STREET
NEW YORK, NY 10036
      See attached Exhibit.
SHAW DAVID E
39TH FLOOR, TOWER 45
120 WEST FORTY-FIFTH STREET
NEW YORK, NY 10036
      See attached Exhibit.

Signatures

D. E. Shaw Valence Portfolios, L.L.C. By: D. E. Shaw & Co., L.P., as managing member By: Eric Wepsic, Managing Director 03/12/2007
**Signature of Reporting Person Date

D. E. Shaw & Co., L.P., as managing member By: Eric Wepsic, Managing Director 03/12/2007
**Signature of Reporting Person Date

David E. Shaw By: Eric Wepsic, Attorney-in-Fact for David E. Shaw 03/12/2007
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) D. E. Shaw Valence Portfolios, L.L.C. ("Valence") beneficially owns 51,600 shares of the Common Stock reported in Table 1 in the name of D. E. Shaw Valence L.L.C. ("Valence LLC"). Valence beneficially owns all of the options reported in Table 2 in the name of Valence LLC.
(2) The securities of the Issuer to which this form relates are held directly by Valence, except as described in footnote 2. D. E. Shaw & Co., L.P. ("DESCO LP") (as managing member of and investment adviser to Valence) and Mr. David E. Shaw ("David E. Shaw") (as president and sole shareholder of D. E. Shaw & Co., Inc., which is the general partner of DESCO LP), may be deemed to be the beneficial owners of the Common Stock of the Issuer held by Valence for purposes of Rule 16a-1(a) of the Securities Exchange Act of 1934, as amended. (Continued in footnote 3)
(3) In accordance with instruction 4(b)(iv), the entire number of shares of Common Stock that may be deemed to be beneficially owned by David E. Shaw or DESCO LP is reported herein. Each of DESCO LP and David E. Shaw disclaims any beneficial ownership of any of the securities listed in this Form 3, except to the extent of any pecuniary interest therein.
(4) The derivative securities that reference this footnote are immediately exercisable "American-style" options.
 
Remarks:
See attachment for explanation of relationship of Reporting Persons to Issuer.

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