Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

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Item 1.

(a)

Name of Issuer

         EXACT Sciences Corp

(b)

Address of Issuer's Principal Executive Offices

100 Campus Drive
Marlborough, MA 01752

Item 2.

(a)

Name of Person Filing

Mazama Capital Management, Inc.

(b)

Address of Principal Business Office or, if none, Residence

One S.W. Columbia, Suite 1500, Portland, Oregon 97258

(c)

Citizenship

State of Oregon

(d)

Title of Class of Securities

Class A Common

(e)

CUSIP Number

30063P105

Item 3.

If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

(a)

[    ]

Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).

(b)

[    ]

Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

(c)

[    ]

Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).

(d)

[    ]

Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C 80a-8).

(e)

[ X ]

An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E);

(f)

[    ]

An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F);

(g)

[    ]

A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);

(h)

[    ]

A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

(i)

[    ]

A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

(j)

[    ]

Group, in accordance with §240.13d-1(b)(1)(ii)(J).

Item 4.

Ownership.

(a)

Amount beneficially owned:

         521300

(b)

Percent of class:

         1.98%

(c)

Number of shares as to which the person has:

(i)

Sole power to vote or to direct the vote

         300400

(ii)

Shared power to vote or to direct the vote

         0

(iii)

Sole power to dispose or to direct the disposition of

         521300

(iv)

Shared power to dispose or to direct the disposition of

         0

Item 5.

Ownership of Five Percent or Less of a Class

          If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following [ X ].

Instruction: Dissolution of a group requires a response to this item.

         This statement is being filed to report the fact that as of the date hereof, the reporting person has ceased to be the beneficial owner of more than 5 percent of Exact Sciences Corp. stock.

Item 6.

Ownership of More than Five Percent on Behalf of Another Person

                  N/A

Item 7.

Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company

                  N/A

Item 8.

Identification and Classification of Members of the Group

                  N/A

Item 9.

Notice of Dissolution of Group

Item 10.

Certification

        After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

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